Hepatoprotective Effect of Green Tea (Camellia sinensis) Extract against Tamoxifen-induced Liver Injury in Rats

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Hepatoprotective effect of green tea (Camellia sinensis) extract against tamoxifen-induced liver injury in rats.

Tamoxifen citrate (TAM), is widely used for treatment of breast cancer. It showed a degree of hepatic carcinogenesis. The purpose of this study was to elucidate the antioxidant capacity of green tea (Camellia sinensis) extract (GTE) against TAM-induced liver injury. A model of liver injury in female rats was done by intraperitoneal injection of TAM in a dose of 45mg Kg(-1) day(-1), i.p. for 7 s...

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A biochemical study on ameliorative effect of green tea (Camellia sinensis) extract against contrast media induced acute kidney injury

INTRODUCTION Reactive oxygen species have been shown to be mediators of kidney injury and green tea polyphenols are potent-free radical scavengers. OBJECTIVES In this study we sought to examine whether green tea was able to protect renal toxicity induced by contrast media or not. MATERIALS AND METHODS In this experimental study 40 rats were randomly divided into four groups including: 1) co...

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the effect of aqueous extract of garlic on formalin-induced pain in male rats

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Green tea extract (Camellia sinensis) fermented by Lactobacillus fermentum attenuates alcohol-induced liver damage.

Here, the impact of an extract derived from green tea (Camellia sinensis) and fermentation with Lactobacilli fermentum strain OCS19 was explored with acute alcohol-induced liver damage. The study employed the HepG2 hepatic cell line and an in vivo murine model of liver damage. L. fermentum-fermented green tea extract (FGTE) was found to possess pronounced alcohol metabolizing enzyme activity. I...

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Anti-Acanthamoeba effect of Camellia sinensis extract (black and green tea) in vitro

Background: Acanthamoeba is a resistant protozoan that causes severe diseases, such as GAE and CAK. Because many medications are ineffective on the parasite, the quest to find alternative drugs is in progress. Objective: This research was aim 13 ed to assess the performance of the black and green tea extracts on Acanthamoeba. Methods: The clinical isolate of Aca...

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ژورنال

عنوان ژورنال: BMB Reports

سال: 2005

ISSN: 1976-6696

DOI: 10.5483/bmbrep.2005.38.5.563